Esophageal and Gastric Cancer Regulator of HLA-A Expression in The MAPK Pathway Is a Predominant
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چکیده
منابع مشابه
The MAPK pathway is a predominant regulator of HLA-A expression in esophageal and gastric cancer.
Downregulation of HLA class I expression may contribute to a poor prognosis in cancer patients. There is limited information about epigenetic and oncogenic regulation of HLA class I, and multiple mechanisms may be involved. In the current study, we examined the relationship between the HER2-signaling pathway (MAPK and PI3K-Akt) and the expression of HLA class I and Ag-processing machinery (APM)...
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تاریخ انتشار 2013